Protein Labeling Reagents
Biotium Phalloidin, CF405M, 300 U
Phalloidin conjugates are actin filament stains for fixed and permeabilized cells. CF dyes are Biotium's line of next-generation fluorescent dyes with advantages in brightness, photostability, and conjugate specificity compared to other fluorescent dyes. Blue fluorescent CF405M has excitation/emission at 408/452 nm.
Biotium Tyramide Amplification Kit with HRP Streptavidin and CF640R Tyramide
Tyramide amplification, sometimes called Catalyzed Reporter Deposition (CARD), is an enzyme-mediated detection method that uses the catalytic activity of horseradish peroxidase (HRP) to generate high density labeling of a target protein or nucleic acid sequence in situ. The tyramide amplification method has been reported to increase the sensitivity by up to 100-fold compared to the conventional avidin-biotinylated complex procedure. The kit contains HRP streptavidin CF640R dye tyramide. The dye has an excitation/emission of 642/662 nm. The kit contains sufficient reagent for 50-150 slides.
Biotium CF647 Protein Labeling Kit , 3x(1mg) labelings
This kit contains everything you need to label antibodies or other proteins with a fluorescent CF dye succinimidyl ester (CF dye SE). Each kit contains reagents for three labeling reactions of up to 1 mg protein per reaction. CF dyes are Biotium's line of next-generation fluorescent dyes with advantages in brightness, photostability, and conjugate specificity compared to other fluorescent dyes. Far-red fluorescent CF647 dye has excitation/emission at 650/665 nm.
Enzo Life Sciences Rhod-2 AM (ultra pure) (1mg). CAS: 129787-64-0
Rhod-2 AM has the longest fluorescent emission signal of the commonly used calcium indicators. It contains a rhodamine-like fluorophore, making it suitable for use with argon and krypton laser excitation sources. Rhod-2 signal intensity one of the strongest of all the calcium probes. Rhod 2 is especially suitable probe for intracellular calcium monitoring by confocal laser-scanning microscopy and flow cytometry. The dissociation constant of Rhod 2 with calcium is among the highest of all the fluorescent calcium probes, providing a wider range for monitoring calcium concentration. Wavelength Maxima: Excitation 549nm, Emission 578nm. Alternative name: 1-[2-Amino-5-(3-dimethylamino-6-dimethylammonio-9-xanthenyl)phenoxy]-2-(2-amino-5-methylphenoxy)]ethane-N,N,N',N'-tetraacetic acid, tetraacetoxy methyl ester . Br. Purity: ≥90% (HPLC). Solubility: Soluble in DMSO. Long Term Storage: -20°C.
Biotium PLGF(PLGF94), CF488A conjugate, 0.1mg/mL
The onset of angiogenesis is believed to be an early event in tumorigenesis and may facilitate tumor progression and metastasis. Several growth factors with angiogenic activity have been described. These include Fibroblast Growth Factor (FGF), Platelet Derived Growth Factor (PDGF), Vascular Endothelial Growth Factor (VEGF) and Placenta Growth Factor (PLGF). Placenta growth factor (PLGF) is a secreted protein primarily produced by placental trophoblasts but also expressed in other endothelial cells and tumors. There are three isoforms, PLGF-1, PLGF-2, and PLGF-3. PLGF-2 is expressed up until week 8 in the placenta; the placental tissues continuously express PLGF-1 and PLGF-3 but only PLGF-1 is found in colon and mammary carcinomas. PLGF acts to stimulate angiogenesis, endothelial growth and migration. PLGF is a powerful promoter of tumor growth and is upregulated in some cancers, and PLGF is thought to aid in atherosclerotic lesions and neovascular growth surrounding the lesio
Biotium CD13(WM15), CF488A conjugate, 0.1mg/mL
Recognizes an integral membrane glycoprotein of 150 kDa, identified as CD13 (also known as aminopeptidase-N). The antibody recognizes an extracellular epitope. The CD13 antigen is present on most cells of myeloid origin including granulocytes, monocytes, mast cells, and GM-progenitor cells. It is also expressed by the majority of AML, CML in myeloid blast crisis, and in a smaller fraction of lymphoid leukemias. CD13 is absent from normal lymphocytes, platelets and erythrocytes. CD13 is also present on fibroblasts; endothelial cells, epithelial cells from renal proximal tubules and intestinal brush border, bone marrow stromal cells, osteoclasts, and cells lining bile duct canaliculi. CD13 is identical to aminopeptidase N (APN), a prominent membrane-bound metalloprotease present on the surface of intestinal brush border and renal tubules. CD13 plays a role in metabolism of biologically active peptides, in phagocytosis, and in bactericidal/tumoricidal activities. It also serves
Biotium CD32(7.3), CF568 conjugate, 0.1mg/mL
This MAb reacts with a CD32 (FcgRII) epitope (cluster-4). It displays a stronger reaction with Daudi than with U937 cells. The epitope is located in domain 2 of FcgRIIa. Its Fab'2 fragments block immune complex binding. CD32 (FcgRII) is a type 1 transmembrane glycoprotein that mediates several functions including phagocytosis, cytotoxicity, and immunomodulation as well as platelet aggregation. Three genes (A, B, and C) encode CD32 and at least 6 isoforms are generated via alternative mRNA splicing, i.e., IIa1, IIa2, IIb1, IIb2, IIb3 and IIc. Monocytes/macrophages, placental trophoblasts and endothelial cells express all isoforms. In addition, the IIb isoform is expressed by B cells, and the IIa isoform by platelets, granulocytes and, weakly, by B cells. NK cells and neutrophils express Isoform IIc. CD32 binds weakly to the Fc region of monomeric IgG but more strongly to IgG aggregates and immune complexes.Primary antibodies are available purified, or with a selection of fluor
CONJU PROBE LLC BCN-PEG3-MAL (ENDO) | 2141976-33-0 | MFCD31811466 | 25 mg
BCN-PEG3-MAL (ENDO) | Purity: >90% | Mol Wt: 519.59 | 2141976-33-0 | MFCD31811466 | 25 mg
Cytoskeleton, Inc. SiR-NHS Ester, 1mg, SiR-NHS ester is the N-hyroxysuccinimidyl ester of SiR
SiR-NHS ester is the N-hyroxysuccinimidyl ester of SiR. This amine reactive probe enables the preparation of custom SiR probes. SiR-NHS ester can be coupled to any amine bearing ligand: antibody, drug, protein or nucleic acid. SiR is compatible with GFP and/or m-cherry fluorescent proteins. It can be imaged with standard Cy5 filtersets.
Biotium LysoView™ 540, 1000X in DMSO, Trial Size
LysoView™ 540 is a red fluorescent dye that is highly selective for labeling and tracking of lysosomes in live cells, with no wash step required. With absorption and emission at 540/634 nm, the dye can be detected using a Cy3 filter set.
Biotium CF488A Maleimide
CF Dye Maleimides are thiol-reactive fluorescent dyes. Maleimides are commonly used to label proteins on free thiol groups. CF dyes are Biotium's line of next-generation fluorescent dyes with advantages in brightness, photostability, and conjugate specificity compared to other fluorescent dyes. Green fluorescent CF488A dye has excitation/emission at 490/515 nm.
Revvity Health Sciences Inc IVISense 680 NHS Fluorescent Dye (1 mg) (VivoTag)
IVISense 680 NHS Fluorescent Dye (1 mg) (VivoTag)
(F)(F)(F)F.CN1\C(=C\C=C\C2=[N+](CCCCCC(=O)NCC#C)c3ccccc3C2(C)C)C(C)(C)c2ccccc12 | 1mg | 296213729](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502453992.PNG-250.jpg)
eMolecules Cy3 alkyne | Broadpharm |639.667 | C33H40F6N3OP | 96.000 | F[P-](F)(F)(F)(F)F.CN1\C(=C\C=C\C2=[N+](CCCCCC(=O)NCC#C)c3ccccc3C2(C)C)C(C)(C)c2ccccc12 | 1mg | 296213729
Cy3 alkyne | Broadpharm |639.667 | C33H40F6N3OP | 96.000 | F[P-](F)(F)(F)(F)F.CN1\C(=C\C=C\C2=[N+](CCCCCC(=O)NCC#C)c3ccccc3C2(C)C)C(C)(C)c2ccccc12 | 1mg | 296213729